Research Interests
Cancer-related Projects:
Intensive efforts are taking place to determine the structures of various cancer-associated proteins and types of damaged DNA, including oxidative and UV damaged, and, ultimately, to develop anticancer drugs. Using complex crystal structures and binding studies, the search for new anti-cancer drugs that are free of side effects, are being carried out. We are also investigating key plant enzymes involved in various pathways, which have important and direct connections with human health such as chemoprotection against various cancers, lowering blood cholesterol levels, and as antifungal/antiviral agents, biocides, antifeedants, and antioxidants. These studies will be used to develop treatments for various cancers and for prevention of certain allergies.
Antibiotics-related Projects:
One of major challenges for modern medical research is the development of new antibiotics against pathogenic bacteria. We are trying to identify candidates for new antibiotic targets, which is of immense importance for the development of new generation antibiotics.
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