Mixter, Philip
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Instructional Responsibilities

MBioS 305: General Microbiology (Lecture)

MBioS 306: General Microbiology (Lab)

MBioS 540: Immunology

MBioS 410: Medical Microbiology

EdSci 523 Medical Immunology (WWAMI Medical Program)

PharS 540 Immunology and Immunotherapy (Pharmacy Science Program)

Research Interests
I have a long running interest in the response to intestinal pathogens and immunoregulation. In collaboration with Dr. Michael Konkel (SMB) , we have focused on the innate response to Campylobacter jejuni by monocyte white blood cells. This food borne pathogen initiates a rapid inflammatory response that is self-limiting. In a high proportion of patients, a neuropathy develops weeks after recovering from infection. We continue to focus on the dynamic relationship between host and pathogen using molecular tools, tissue culture systems and animal models. In addition, I have a developing interest in science education and effective learning strategies for upper division science courses.

Publications
P.F. Mixter, J.D. Klena, G.A. Flom, A.M. Siegesmund, and M.E. Konkel. 2003. Flow In vivo tracking of Campylobacter jejuni by Using a Novel Recombinant Expressing Green Fluorescent Protein. Applied and Environmental Microbiology 69:2864-2874.

Chew, B.P., C.M. Brown, J.S. Park, and P.F. Mixter. 2003. Dietary Lutein Inhibits Mouse Mammary Tumor Growth By Regulating Angiogenesis And Apoptosis. Inpress Anticancer Research 23:3333-3339.

Siegesmund, A.M., M.E. Konkel and P.F. Mixter. 2004. Campylobacter jejuni Infection ofDifferentiated THP-1 macrophages Results in Simultaneous Interleukin-1-beta Release and Caspase-1-independent Apoptosis. Microbiology 150:561-569.

Redkar,A. P. Mixter, and S.S. Daoud. 2004. Implications of p53 in growth arrest and apoptosis on combined treatment of human mammary epithelial cells with topotecan and UCN-01. J. Exp. Ther Oncol 4: 213-222.

Dahl, J and P.F. Mixter.  2007. “Night Gallery:” An Innovative Multimedia Strategy for Delivering a General Microbiology Lecture. National Association of Biology Teachers, in press.